Purified Anti-Mouse CD62L (L-Selectin) (MEL-14)
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte ārollingā on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin Ī±family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.
The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
| Name | Purified Anti-Mouse CD62L (L-Selectin) (MEL-14) |
|---|---|
| Cat. No. | 70-0621 |
| Alternative Names | LECAM-1, Ly-22 |
| Gene ID | 20343 |
| Clone | MEL-14 |
| Isotype | Rat IgG2a, Īŗ |
| Reactivity | Mouse |
| Format | Purified |
| Application | Flow Cytometry, IHC, IP, Electron Microscopy |
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte ārollingā on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin Ī±family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.
The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
| Name | Purified Anti-Mouse CD62L (L-Selectin) (MEL-14) |
|---|---|
| Cat. No. | 70-0621 |
| Alternative Names | LECAM-1, Ly-22 |
| Gene ID | 20343 |
| Clone | MEL-14 |
| Isotype | Rat IgG2a, Īŗ |
| Reactivity | Mouse |
| Format | Purified |
| Application | Flow Cytometry, IHC, IP, Electron Microscopy |
Original: $108.00
-70%$108.00
$32.40Description
The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte ārollingā on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin Ī±family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.
The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
| Name | Purified Anti-Mouse CD62L (L-Selectin) (MEL-14) |
|---|---|
| Cat. No. | 70-0621 |
| Alternative Names | LECAM-1, Ly-22 |
| Gene ID | 20343 |
| Clone | MEL-14 |
| Isotype | Rat IgG2a, Īŗ |
| Reactivity | Mouse |
| Format | Purified |
| Application | Flow Cytometry, IHC, IP, Electron Microscopy |
